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The idea is to take surviving DNA of an extinct species, and compare it to the genome of a closely-related modern species, then use techniques like CRISPR to edit the modern species' genome in the places where it differs. Great British Bake Off 2023: Sixth contestant to leave is announced after screwing up Technical challenge
BBC and Sky scramble to make on-air apologies for broadcasting Dominic Cummings' expletive-filled Covid inquiry appearance uncensored (but furious viewers blast them for saying sorry while ex-No10 aide gave evidence) Gilbert and colleagues re-sequenced the Christmas Island rat genome and compared it to reference genomes of living members of the Rattus species. “We then explored how evolutionary divergence from the extant reference genome affected the fraction of the Christmas Island rat genome that could be recovered,” the authors write in the paper. Their analyses show that, even when a high-quality genome is used as a reference (the Norway brown rat), almost five percent of the genome sequence is unrecoverable. In total, 1,661 genes were recoverable, and 26 were completely absent. Several of the missing genes are implicated in the rat’s sense of smell, meaning a “de-extinct” version of the Christmas Island rat would not physiologically process smells in an identical manner to the original rat. Our Yorkshire Farm's Amanda Owen 'is using her son Reuben's popularity to bolster her brand as she relaunches TV career after secret affair was exposed'Stacey Solomon, husband Joe Swash and their kids transform into The Wizard of Oz characters as they pose for sweet family snaps on Halloween The team used brown rats, commonly used in lab experiments, as the modern reference species, and found they could reconstruct 95 percent of the Christmas Island rat genome. Kim and Khloe Kardashian dress up in plaid mini skirts as Bratz dolls for Halloween... after Kylie Jenner collaborated with the toy brand MailOnline's complete guide to the MOON: 9 astonishing facts about our lunar satellite that will leave you...
Other, smaller creatures are also candidates. The non-profit Revive & Restore’s five stages of de-extinction plan aims to – as the organization’s name suggests – revive and restore the passenger pigeon to the Eastern forests of the United States. It suggests that reintroducing the pigeon would stimulate cycles of regeneration, making forests more productive and diverse. Run-DMC's Darryl McDaniels reveals he was 'drinking case of Olde English a day' during alcoholism battle - and details suicidal thoughts Scientists reveal what caused the 'catastrophic collapse' that led to the extinction of the dinosaurs 66...Matthew Perry's co-star Rosanna Arquette pays tribute to 'kind and lovely' Friends actor and recalls his love of grape soda after death aged 54 In the near future, Dr Gilbert plans to try doing the actual gene editing on rats but would like to start with species that are still living. Halloween, Hollywood style! Hailey Bieber, Kylie and Kendall Jenner, and Christina Aguilera get into a spooky mood Travis Barker LEAKS name of the son he is expecting with wife Kourtney Kardashian... and reveals the due date too (it's sooner than you think) Strictly's Katya Jones leaves rehearsals with dance partnerNigel Harman as she's seen for the first time since splitting from William Abbotts
Maya Jama looks incredible in a figure hugging leather jumpsuit as she transforms into X-Men superheroStorm for Halloween Lorraine Kelly shares her devastation as young ITV team member battles terminal cancer two months after welcoming a baby boy: 'We are all deeply saddened' Matthew Perry's former fiancée Molly Hurwitz says Friends star 'would love that the world is talking about how talented he was' following his death at 54Gilbert admitted that, while the science was fascinating, he had mixed feelings on de-extinction projects. Godfather' of AI is among hundreds of experts calling for urgent action to prevent the 'potentially catastrophic' risks posed by technology In a new paper, an international team of academics outline how the use of CRISPR – a gene editing technique that can 'cut and paste' small sections of DNA, deleting or repairing flawed genes – could lead to the rat's 'de-extinction'. Teams in Australia meanwhile are looking at reviving the Tasmanian tiger, or thylacine, whose last surviving member died in captivity in 1936. Gilbert said old DNA was like a book that has gone through a shredder, while the genome of a modern species is like an intact "reference book" that can be used to piece together the fragments of its degraded counterpart.
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